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AFFINITYDIRECT

Compounded Tirzepatide

A once-weekly dual-receptor injection that acts on two hunger-regulating pathways, compounded with B12, Glycine, B6, and L-Carnitine — $329/month at any prescribed dose.

Check Your Eligibility →From $329/mo · Free medical review

Transparent pricing

Pricing

Any dose

Tirzepatide

Dual GIP + GLP-1 receptor agonist — one price at every dose

$329/month
  • Want dual-action (GIP + GLP-1) therapy
  • Prior GLP-1 experience with plateaued results
  • Prefer flat pricing across every dose
Check eligibility →

Charged at checkout · full refund if not approved

The science

How it works

Dual GIP + GLP-1 receptor agonist

Tirzepatide activates both the GLP-1 receptor (appetite, fullness, gastric emptying) and the GIP receptor (a second incretin pathway involved in how the body handles nutrients). The dual mechanism is why its trial results are the strongest published in the class.

Compounded with metabolic cofactors

Our pharmacy compounds tirzepatide with vitamin B12, Glycine, B6, and L-Carnitine based on patient medical needs — cofactors involved in energy metabolism commonly paired with GLP-1 therapy.

Flat pricing across titration

Tirzepatide titrates from low starting doses to higher maintenance doses over several months. At Affinity the monthly price does not change as your provider raises your dose.

SURMOUNT-1 trial

Up to ~21% average body-weight loss

Jastreboff et al., NEJM (2022) — SURMOUNT-1

In the SURMOUNT-1 trial of the FDA-approved branded version (highest dose alongside diet and exercise), adults lost an average of up to about 21% of body weight over 72 weeks. Individual results vary and no outcome is guaranteed; compounded tirzepatide is a separate, non-FDA-approved preparation.

Safety first

Taking it safely

Administration basics

  • Once-weekly subcutaneous self-injection, any consistent day of the week
  • Inject into the abdomen, thigh, or upper arm; rotate sites
  • Refrigerate the vial; supplies (syringes, alcohol prep pads) are included
  • Your provider sets and adjusts your dose — never change it on your own

Common side effects

Nausea (usually early or after dose increases) · Diarrhea or constipation · Reduced appetite · Indigestion · Injection-site irritation

When to contact a provider

  • Severe or persistent abdominal pain (possible pancreatitis) — seek care promptly
  • Symptoms of gallbladder problems (right-upper abdominal pain, fever, jaundice)
  • Severe vomiting or diarrhea leading to dehydration
  • Signs of an allergic reaction (swelling, trouble breathing) — call 911

This is educational information, not a complete safety profile. Your provider reviews your full history before prescribing and remains available throughout treatment.

Good to know

Compounded Tirzepatide — questions

Semaglutide or tirzepatide — which is right for me?

That is your provider’s call after reviewing your intake. Broadly: semaglutide is the most-prescribed starting point with the lower entry price; tirzepatide’s dual mechanism posted stronger average trial results and is often considered when prior GLP-1 results plateaued. Your provider weighs your history, tolerance, and goals.

Why is it one price at any dose?

Because tirzepatide doses titrate up over time, per-dose pricing gets more expensive exactly when patients are established on therapy. Our flat $329/month covers any prescribed dose, so your cost never changes as your provider adjusts treatment.

What happens if I stop?

Appetite generally returns toward baseline, and weight regain is common without continued lifestyle change. Talk to your provider before stopping.

Comparing options? See Compounded Semaglutide or the side-by-side comparison.

See if you qualify.

Two-minute eligibility check. Charged only at checkout — full refund if a provider doesn't approve treatment.

Medical Disclosure

Important safety information: Compounded semaglutide and compounded tirzepatide are prepared by licensed U.S. compounding pharmacies and are not FDA-approved. The FDA does not review compounded medications for safety, effectiveness, or quality before they are dispensed. Prescription weight-loss medication is only available if a licensed provider determines it is appropriate for you after reviewing your health intake. Individual results vary and no amount of weight loss is guaranteed. GLP-1 medications should be used alongside a reduced-calorie diet and increased physical activity.